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CHICAGO Chaussures Homme Nike Air Presto Flyknit Ultra Bleu Pas Cher , Jan. 2 (Xinhua) -- A sleepless night causes levels of the Alzheimer's protein amyloid beta to rise faster than the brain's waste-disposal system can remove it, a study of Washington University School of Medicine in St. Louis found.


Persistent high levels of the protein can set off a cascade of brain changes leading to dementia.


Researchers at the university studied eight people aged 30 to 60 with no sleep or cognitive problems. The participants were assigned randomly to one of three scenarios: having a normal night's sleep without any sleep aids; staying up all night; or sleeping after treatment with sodium oxybate, a prescription medication for sleep disorders.


Each scenario occurred during 36 hours of monitoring Chaussures Homme Nike Air Presto Flyknit Ultra Rouge Pas Cher , starting in the morning and continuing through the afternoon of the following day. The researchers took samples of the fluid that surrounds the brain and spinal cord every two hours to monitor how amyloid beta levels change with time of day and tiredness.


All eight participants returned four to six months later to undertake a second scenario, and four people completed all three.


Amyloid beta levels in sleep-deprived people were 25 to 30 percent higher than in those who had slept the night through. After a sleepless night, amyloid beta levels were on par with the levels seen in people genetically predisposed to develop Alzheimer's at a young age.


"This study is the clearest demonstration in humans that sleep disruption leads to an increased risk of Alzheimer's disease through an amyloid beta mechanism Chaussures Homme Nike Air Presto Flyknit Ultra Blanche Pas Cher ," said senior author Randall Bateman, professor of neurology at Washington University in St. Louis.


One sleepless night probably has no effect on overall risk of Alzheimer's. Researchers are much more concerned about people with chronic sleep problems.


When amyloid beta levels in the brain are persistently high, the protein is more likely to start collecting into plaques. Such plaques damage nearby neurons and can trigger a cascade of destructive brain changes. The brains of people with Alzheimer's disease are dotted with such plaques.


In the study Nike Cortez Classic Nylon Noir Blanche Chaussures Pas Cher , people who took sleep medication had levels of amyloid beta no lower than people who had slept normally.


An estimated 50 million to 70 million American adults struggle to get a good night's sleep. Some have medical conditions such as sleep apnea.


Further studies are needed to determine whether improving sleep in people with sleep problems can reduce amyloid beta levels and risk of Alzheimer's disease.


The study has been published online in Annals of Neurology.




BEIJING, Jan. 8 (Xinhua) -- Senior officials of the Communist Party of China (CPC) attending a workshop at the Party School of the CPC Central Committee have been urged to "resolutely defend General Secretary Xi Jinping's core status in the CPC Central Committee and the whole Party."


Wang Huning, a member of the Standing Committee of the Political Bureau of the CPC Central Committee Nike Cortez Classic Nylon PRM Royal Bleu Chaussures Pas Cher , made the remarks Monday at the closing of the workshop attended by newly-elected members and alternate members of the CPC Central Committee, as well as provincial and ministerial-level officials.


"Senior officials must uphold the authority of the Central Committee and its centralized and unified leadership, and align themselves with the Central Committee with Comrade Xi Jinping at the core in terms of political stance Homme Nike Cortez Classic Nylon Deep Bleu Blanche Chaussures Pas Cher , direction, principle and path," Wang said.


The four-day workshop focused on "Xi Jinping Thought on Socialism with Chinese Characteristics for a New Era" and the spirit of the 19th CPC National Congress.


Wang stressed the importance of in-depth understanding of "Xi Jinping Thought on Socialism with Chinese Characteristics for a New Era" with a historical perspective.


"We should take consideration of the historic achievements and profound changes the Party and the country have witnessed Nike Cortez Ultra Breathe Woven Mesh Rouge Noir Chaussures Pas Cher , the striving history of the CPC and the history of the Chinese nation, as well as the evolution of socialism worldwide and the development of human society," he said.


The officials were also told to strengthen their consciousness of the need to think in big-picture terms and implement the goals set at the 19th CPC National Congress.


Wang asked them to fully grasp the new requirements and to use what they learned at the workshop to continue to uphold and develop socialism with Chinese characteristics in the new era.




BRUSSELS, June 29 (Xinhua) -- European leaders on Tuesday pressed for a quick and clear British departure plan to quell worldwide anxiety about the continent's future.


Britain's vote to leave the European Union (EU) last week has unleashed financial and political turmoil not only in the country but across the EU.


In a summit in Brussels, European leaders pushed Britain toward the exit door, warning British Prime Minister David Cameron that there's no turning back after his country's unprecedented vote to leave the bloc. The following are some quotes by EU leaders:


-- German Chancellor Angela Merkel:


I want to say very clearly tonight that I see no way to reverse the decision. We would do well to accept this reality.


The atmosphere was serious, amicable and borne by the awareness that


this is more of a sad event, but that it is a reality.


Whoever wants to leave this family cannot expect to have no more obligations, but to keep privileges.


-- French President Francois Hollande:


Single market access depended on accepting the the four freedoms of movement of goods, capital, labor and services.


If they don't want free movement, they won't have access to the internal market.


-- Luxembourg Prime Minister Xavier Bettel:


We are not on Facebook, where things are complicated. We are married or divorced, but not something in betwe.
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